학술논문
A network analysis to identify mediators of germline-driven differences in breast cancer prognosis
Document Type
article
Author
Maria Escala-Garcia; Jean Abraham; Irene L. Andrulis; Hoda Anton-Culver; Volker Arndt; Alan Ashworth; Paul L. Auer; Päivi Auvinen; Matthias W. Beckmann; Jonathan Beesley; Sabine Behrens; Javier Benitez; Marina Bermisheva; Carl Blomqvist; William Blot; Natalia V. Bogdanova; Stig E. Bojesen; Manjeet K. Bolla; Anne-Lise Børresen-Dale; Hiltrud Brauch; Hermann Brenner; Sara Y. Brucker; Barbara Burwinkel; Carlos Caldas; Federico Canzian; Jenny Chang-Claude; Stephen J. Chanock; Suet-Feung Chin; Christine L. Clarke; Fergus J. Couch; Angela Cox; Simon S. Cross; Kamila Czene; Mary B. Daly; Joe Dennis; Peter Devilee; Janet A. Dunn; Alison M. Dunning; Miriam Dwek; Helena M. Earl; Diana M. Eccles; A. Heather Eliassen; Carolina Ellberg; D. Gareth Evans; Peter A. Fasching; Jonine Figueroa; Henrik Flyger; Manuela Gago-Dominguez; Susan M. Gapstur; Montserrat García-Closas; José A. García-Sáenz; Mia M. Gaudet; Angela George; Graham G. Giles; David E. Goldgar; Anna González-Neira; Mervi Grip; Pascal Guénel; Qi Guo; Christopher A. Haiman; Niclas Håkansson; Ute Hamann; Patricia A. Harrington; Louise Hiller; Maartje J. Hooning; John L. Hopper; Anthony Howell; Chiun-Sheng Huang; Guanmengqian Huang; David J. Hunter; Anna Jakubowska; Esther M. John; Rudolf Kaaks; Pooja Middha Kapoor; Renske Keeman; Cari M. Kitahara; Linetta B. Koppert; Peter Kraft; Vessela N. Kristensen; Diether Lambrechts; Loic Le Marchand; Flavio Lejbkowicz; Annika Lindblom; Jan Lubiński; Arto Mannermaa; Mehdi Manoochehri; Siranoush Manoukian; Sara Margolin; Maria Elena Martinez; Tabea Maurer; Dimitrios Mavroudis; Alfons Meindl; Roger L. Milne; Anna Marie Mulligan; Susan L. Neuhausen; Heli Nevanlinna; William G. Newman; Andrew F. Olshan; Janet E. Olson; Håkan Olsson; Nick Orr; Paolo Peterlongo; Christos Petridis; Ross L. Prentice; Nadege Presneau; Kevin Punie; Dhanya Ramachandran; Gad Rennert; Atocha Romero; Mythily Sachchithananthan; Emmanouil Saloustros; Elinor J. Sawyer; Rita K. Schmutzler; Lukas Schwentner; Christopher Scott; Jacques Simard; Christof Sohn; Melissa C. Southey; Anthony J. Swerdlow; Rulla M. Tamimi; William J. Tapper; Manuel R. Teixeira; Mary Beth Terry; Heather Thorne; Rob A. E. M. Tollenaar; Ian Tomlinson; Melissa A. Troester; Thérèse Truong; Clare Turnbull; Celine M. Vachon; Lizet E. van der Kolk; Qin Wang; Robert Winqvist; Alicja Wolk; Xiaohong R. Yang; Argyrios Ziogas; Paul D. P. Pharoah; Per Hall; Lodewyk F. A. Wessels; Georgia Chenevix-Trench; Gary D. Bader; Thilo Dörk; Douglas F. Easton; Sander Canisius; Marjanka K. Schmidt
Source
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Subject
Language
English
ISSN
2041-1723
Abstract
In breast cancer the contribution of different genetic variants to disease heritability is complex and not fully understood. Here, the authors present a network-based analysis in 84,567 patients studying ~7.3 million variants, identifying gene modules associated with breast cancer survival.