학술논문

Capture Hi-C identifies putative target genes at 33 breast cancer risk loci
Document Type
article
Source
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
Risk loci for breast cancer have been identified by genome-wide association studies. Here, the authors use Capture Hi-C to identify 110 putative target genes at 33 loci and assessed associations of gene expression, SNP genotype, and survival, providing evidence of mechanisms that may influence the prognosis and risk of breast cancer.