학술논문

Clinical Characteristics of Corynebacterium Bacteremia Caused by Different Species, Japan, 2014–2020
Document Type
article
Source
Emerging Infectious Diseases, Vol 27, Iss 12, Pp 2981-2987 (2021)
Subject
Corynebacterium striatum
Corynebacterium jeikeium
contamination rate
bacteremia
hematologic malignancy
bacteria
Medicine
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
1080-6040
1080-6059
Abstract
To determine differences in clinical characteristics of patients with bacteremia caused by Corynebacterium striatum, C. jeikeium, and other species of Corynebacterium, we retrospectively reviewed medical records of patients in Japan who had Corynebacterium bacteremia during January 2014–May 2020. Of the 115 records evaluated, 60 (52%) were cases of true bacteremia and 55 (48%) were cases of contamination. Proportions of true bacteremia cases caused by C. striatum (70%) and by C. jeikeium (71%) were significantly higher than those caused by other species of Corynebacterium (9%). These 2 organisms were commonly detected in blood cultures of patients with hematologic malignancies and neutropenia. The mortality rates at 90 days were 34% (C. striatum), 30% (C. jeikeium), and 0 (other species). Given the high mortality rates, assessing true bacteremia when C. striatum or C. jeikeium is detected in blood cultures, especially in patients with hematologic malignancy, is warranted.