학술논문

Recurrent reactive hypoglycemia due to clozapine‐induced glucose intolerance: A case report
Document Type
article
Source
PCN Reports, Vol 2, Iss 4, Pp n/a-n/a (2023)
Subject
diabetes
impaired glucose tolerance
insulin
oral glucose tolerance test
voglibose
Psychiatry
RC435-571
Language
English
ISSN
2769-2558
Abstract
Abstract Background Although diabetes is one of the most common side effects of clozapine, a medication for the treatment of schizophrenia, to the best of our knowledge no study exists on clozapine‐induced glucose intolerance or hypoglycemia in patients with schizophrenia. Case Presentation We report a case of schizophrenia with repeated reactive hypoglycemia due to abnormal glucose tolerance during clozapine treatment. During clozapine administration in patients with schizophrenia, it is necessary to monitor physical and psychiatric symptoms due to reactive hypoglycemia and hyperglycemia. If abnormal glucose tolerance is a concern, it should be promptly detected using blood or oral glucose tolerance tests. Conclusion Early intervention for impaired glucose tolerance may prevent clozapine discontinuation due to diabetes or hyperglycemia.