학술논문
Severe nocturnal and postexercise hypoxia in children and adolescents with sickle cell disease.
Document Type
article
Author
Source
PLoS ONE, Vol 9, Iss 5, p e97462 (2014)
Subject
Language
English
ISSN
1932-6203
Abstract
Hypoxia is a common feature in children with sickle cell disease (SCD) that is inconsistently associated with painful crises and acute chest syndrome. To assess the prevalence and risk factors of hypoxia, we recorded daytime, nocturnal, and postexercise pulse oximetry (SpO2) values in 39 SCD patients with a median age of 10.8 years. Median daytime SpO2 was 97% (range, 89%-100%), and 36% of patients had daytime hypoxia defined as SpO2