학술논문
Assessment of Osteoporosis with Aspartate Aminotransferase to Platelet Ratio Index Score in Patients of Chronic Liver Disease
Document Type
article
Author
Source
Pakistan Armed Forces Medical Journal, Vol 73, Iss 3 (2023)
Subject
Language
English
ISSN
0030-9648
2411-8842
2411-8842
Abstract
Objective: to assess Osteoporosis with APRI score (aspartate aminotransferase to platelet ratio index) in patients with chronic liver disease. Study Design: Cross-sectional study. Study Setting and Duration: Pak Emirates Military Hospital Rawalpindi, Pakistan from Jan to Dec 2021. Methodology: All Adult patients aged 18 years and above with clinical and imaging features suggestive of chronic liver disease were included in the study. APRI score calculated as the ratio of aspartate aminotransferase to platelet based on the laboratory analysis of Aspartate aminotransferase (AST) and platelet levels was done. Furthermore, a bone density scan (DEXA scan) was also carried out for all the study participants. Results: One hundred and sixty patients fulfilling the inclusion criteria were included. Of the total 160 cases, 53(33.1%) had normal bone density on DEXA scans, 43(26.9%) had Osteopenia and 64(40%) had Osteoporosis. Twenty-nine cases of chronic liver disease cases (25%) had APRI scores 0.3 and0.5 and 1.5 and 2. The significant (p