학술논문
Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease
Document Type
article
Author
Source
Pulmonary Circulation, Vol 10 (2020)
Subject
Language
English
ISSN
2045-8940
20458940
20458940
Abstract
Trichloroethylene exposure is a major risk factor for pulmonary veno-occlusive disease. We demonstrated that trichloroethylene alters the endothelial barrier integrity, at least in part, through vascular endothelial (VE)-Cadherin internalisation, and suggested that this mechanism may play a role in the development of pulmonary veno-occlusive disease.