학술논문

Post-fever retinitis – Newer concepts
Document Type
article
Source
Indian Journal of Ophthalmology, Vol 68, Iss 9, Pp 1775-1786 (2020)
Subject
chikungunya
dengue
post-fever retinitis
rickettsia
systemic steroids
typhoid
west nile virus
zika virus
Ophthalmology
RE1-994
Language
English
ISSN
0301-4738
1998-3689
Abstract
Post-fever retinitis (PFR) is an infectious or para-infectious uveitic entity caused by bacterial or viral agents and seen mainly in tropical countries. Systemic symptoms such as joint pain, skin rash are common during the febrile stage. On the basis of only clinical presentation, it is difficult to pin-point the exact etiology for PFR. Serological investigations, polymerase chain reaction, and knowledge of concurrent epidemics in the community may help to identify the etiological organism. Bacterial causes of PFR such as rickettsia and typhoid are treated with systemic antibiotics, with or without systemic steroid therapy, whereas PFR of viral causes such as chikungunya, dengue, West Nile virus, and Zika virus have no specific treatment and are managed with steroids. Nevertheless, many authors have advocated mere observation and the uveitis resolved with its natural course of the disease. In this article, we have discussed the clinical features, pathogenesis, investigations, and management of PFR.