학술논문
Application of a genetic signature of late GU toxicity in SCIMITAR, a Post-op SBRT trial
Document Type
article
Author
Source
Clinical and Translational Radiation Oncology, Vol 39, Iss , Pp 100594- (2023)
Subject
Language
English
ISSN
2405-6308
Abstract
Predictors of genitourinary toxicity after post-prostatectomy radiotherapy remain elusive. A previously defined germline DNA signature (PROSTOX) has shown predictive ability for late grade ≥ 2 GU toxicity after intact prostate stereotactic body radiotherapy. We explore whether PROSTOX would predict toxicity among patients receiving post-prostatectomy SBRT on a phase II clinical trial.