학술논문
Analysis of immunization time, amplitude, and adverse events of seven different vaccines against SARS-CoV-2 across four different countries
Document Type
article
Author
Maria Elena Romero-Ibarguengoitia; Arnulfo González-Cantú; Chiara Pozzi; Riccardo Levi; Maximiliano Mollura; Riccardo Sarti; Miguel Ángel Sanz-Sánchez; Diego Rivera-Salinas; Yodira Guadalupe Hernández-Ruíz; Ana Gabriela Armendariz-Vázquez; Gerardo Francisco Del Rio-Parra; Irene Antonieta Barco-Flores; Rosalinda González-Facio; Elena Azzolini; Riccardo Barbieri; Alessandro Rodrigo de Azevedo Dias; Milton Henriques Guimarães Júnior; Alessandra Bastos-Borges; Cecilia Acciardi; Graciela Paez-Bo; Mauro Martins Teixeira; Maria Rescigno
Source
Frontiers in Immunology, Vol 13 (2022)
Subject
Language
English
ISSN
1664-3224
Abstract
BackgroundScarce information exists in relation to the comparison of seroconversion and adverse events following immunization (AEFI) with different SARS-CoV-2 vaccines. Our aim was to correlate the magnitude of the antibody response to vaccination with previous clinical conditions and AEFI.MethodsA multicentric comparative study where SARS-CoV-2 spike 1-2 IgG antibodies IgG titers were measured at baseline, 21-28 days after the first and second dose (when applicable) of the following vaccines: BNT162b2 mRNA, mRNA-1273, Gam-COVID-Vac, Coronavac, ChAdOx1-S, Ad5-nCoV and Ad26.COV2. Mixed model and Poisson generalized linear models were performed.ResultsWe recruited 1867 individuals [52 (SD 16.8) years old, 52% men]. All vaccines enhanced anti-S1 and anti-S2 IgG antibodies over time (p