학술논문

Pathogenicity and virulence of Aspergillus fumigatus
Document Type
article
Source
Virulence, Vol 14, Iss 1 (2023)
Subject
Aspergillus fumigatus
Aspergillosis
Virulence factors
Pathogenicity
at-risk factors
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
21505594
2150-5608
2150-5594
Abstract
ABSTRACTPulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major cause of morbidity and mortality globally. Compromised lung defences arising from immunosuppression, chronic respiratory conditions or more recently, concomitant viral or bacterial pulmonary infections are recognised risks factors for the development of pulmonary aspergillosis. In this review, we will summarise our current knowledge of the mechanistic basis of pulmonary aspergillosis with a focus on emerging at-risk populations.