학술논문

Outcomes and risks in palliative pancreatic surgery: an analysis of the German StuDoQ|Pancreas registry
Document Type
article
Source
BMC Surgery, Vol 22, Iss 1, Pp 1-11 (2022)
Subject
Pancreatic ductal adenocarcinoma
Explorative surgery
Palliative surgery
Biliary bypass
Gastroenteric bypass
Registry analysis
Surgery
RD1-811
Language
English
ISSN
1471-2482
Abstract
Abstract Background Non-resectability is common in patients with pancreatic ductal adenocarcinoma (PDAC) due to local invasion or distant metastases. Then, biliary or gastroenteric bypasses or both are often established despite associated morbidity and mortality. The current study explores outcomes after palliative bypass surgery in patients with non-resectable PDAC. Methods From the prospectively maintained German StuDoQ|Pancreas registry, all patients with histopathologically confirmed PDAC who underwent non-resective pancreatic surgery between 2013 and 2018 were retrospectively identified, and the influence of the surgical procedure on morbidity and mortality was analyzed. Results Of 389 included patients, 127 (32.6%) underwent explorative surgery only, and a biliary, gastroenteric or double bypass was established in 92 (23.7%), 65 (16.7%) and 105 (27.0%). After exploration only, patients had a significantly shorter stay in the intensive care unit (mean 0.5 days [SD 1.7] vs. 1.9 [3.6], 2.0 [2.8] or 2.1 [2.8]; P