학술논문
A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cells
Document Type
article
Author
Source
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Subject
Language
English
ISSN
2399-3642
Abstract
Margaret O’Connor et al. report a new Innate Lymphoid Cell population in human tonsils and lymph nodes that inhibit the functional interaction of follicular helper T cells and germinal center B cells. They show that this cell population is expanded under chronic HIV infection and results in decreased antibody production, suggesting a potential role for these cells in diseases with dysregulated immune responses.