학술논문
Clonal hematopoiesis is associated with risk of severe Covid-19
Document Type
article
Author
Kelly L. Bolton; Youngil Koh; Michael B. Foote; Hogune Im; Justin Jee; Choong Hyun Sun; Anton Safonov; Ryan Ptashkin; Joon Ho Moon; Ji Yeon Lee; Jongtak Jung; Chang Kyung Kang; Kyoung-Ho Song; Pyoeng Gyun Choe; Wan Beom Park; Hong Bin Kim; Myoung-don Oh; Han Song; Sugyeong Kim; Minal Patel; Andriy Derkach; Erika Gedvilaite; Kaitlyn A. Tkachuk; Brian J. Wiley; Ireaneus C. Chan; Lior Z. Braunstein; Teng Gao; Elli Papaemmanuil; N. Esther Babady; Melissa S. Pessin; Mini Kamboj; Luis A. Diaz; Marc Ladanyi; Michael J. Rauh; Pradeep Natarajan; Mitchell J. Machiela; Philip Awadalla; Vijai Joseph; Kenneth Offit; Larry Norton; Michael F. Berger; Ross L. Levine; Eu Suk Kim; Nam Joong Kim; Ahmet Zehir
Source
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
Clonal haematopoiesis (CH) has been associated with altered inflammatory profiles and increased risk of cardiovascular and malignant diseases. Here, the authors analyze patient data from two different cohorts and show that CH is associated with severe infections and severe Covid19.