학술논문
European polygenic risk score for prediction of breast cancer shows similar performance in Asian women
Document Type
article
Author
Weang-Kee Ho; Min-Min Tan; Nasim Mavaddat; Mei-Chee Tai; Shivaani Mariapun; Jingmei Li; Peh-Joo Ho; Joe Dennis; Jonathan P. Tyrer; Manjeet K. Bolla; Kyriaki Michailidou; Qin Wang; Daehee Kang; Ji-Yeob Choi; Suniza Jamaris; Xiao-Ou Shu; Sook-Yee Yoon; Sue K. Park; Sung-Won Kim; Chen-Yang Shen; Jyh-Cherng Yu; Ern Yu Tan; Patrick Mun Yew Chan; Kenneth Muir; Artitaya Lophatananon; Anna H. Wu; Daniel O. Stram; Keitaro Matsuo; Hidemi Ito; Ching Wan Chan; Joanne Ngeow; Wei Sean Yong; Swee Ho Lim; Geok Hoon Lim; Ava Kwong; Tsun L. Chan; Su Ming Tan; Jaime Seah; Esther M. John; Allison W. Kurian; Woon-Puay Koh; Chiea Chuen Khor; Motoki Iwasaki; Taiki Yamaji; Kiak Mien Veronique Tan; Kiat Tee Benita Tan; John J. Spinelli; Kristan J. Aronson; Siti Norhidayu Hasan; Kartini Rahmat; Anushya Vijayananthan; Xueling Sim; Paul D. P. Pharoah; Wei Zheng; Alison M. Dunning; Jacques Simard; Rob Martinus van Dam; Cheng-Har Yip; Nur Aishah Mohd Taib; Mikael Hartman; Douglas F. Easton; Soo-Hwang Teo; Antonis C. Antoniou
Source
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Subject
Language
English
ISSN
2041-1723
Abstract
Polygenic risk scores predict the likelihood that an individual will develop a certain cancer, however these are often specific for a given population. Here, the authors show that a risk score developed to assess the risk of breast cancer in European women can also predict risk in Asian populations.