학술논문

Serogroup C invasive meningococcal disease in the post-vaccine era and vaccine failures
Document Type
article
Source
Anales de Pediatría (English Edition), Vol 93, Iss 6, Pp 396-402 (2020)
Subject
Enfermedad meningocócica invasiva
Epidemiología
Reacción en cadena de la polimerasa
Meningococo serogrupo C
Meningococo serogrupo B
Vacuna conjugada antimeningocócica C
Pediatrics
RJ1-570
Language
Spanish; Castilian
ISSN
2341-2879
Abstract
Introduction: The incidence of serogroup C invasive meningococcal disease (IMD) has decreased since the introduction of systematic vaccination in 2000 The aim of this study is to determine the number serogroup C IMD cases diagnosed since then and the vaccine failures. Patients and methods: A retrospective analysis was performed on patients diagnosed with IMD by culture or polymerase chain reaction (PCR) in a maternity and childhood hospital in Barcelona between 2001 and 2018. An analysis was made of the number of vaccine doses and the age received, as well as on the medical records and vaccine cards. Results: There were 128 confirmed cases of IMD (7.1 cases/year; 70.3 in