학술논문

Clinical implications of prolonged hyperglycaemia before basal insulin initiation in type 2 diabetes patients: An electronic medical record database analysis
Document Type
article
Source
Endocrinology, Diabetes & Metabolism, Vol 2, Iss 3, Pp n/a-n/a (2019)
Subject
basal insulin
clinical inertia
glycaemic control
treatment intensification
type 2 diabetes
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Language
English
ISSN
2398-9238
Abstract
Summary Aims To assess the effect of duration of hyperglycaemia before basal insulin (BI) initiation on clinical outcomes in type 2 diabetes (T2D). Materials and methods Patients with T2D who initiated BI during 2009‐2013, had continuous enrolment for ≥2 years preceding and ≥1 year following BI initiation (“index date”), and had ≥1 glycated haemoglobin (A1C) measure not at target (ie, ≥7.0%) within 6 months preindex date were included in the study. Patients were stratified by preindex‐date duration of A1C ≥7.0%. Longitudinal A1C, weight, BMI, and diabetes medication were compared between cohorts for up to 15‐month follow‐up. Results Of 37 053 patients who initiated BI, 40.7%, 15.3%, 16.0%, and 28.0%, respectively, had uncontrolled A1C for