학술논문

Changes in the Composition of the Gut Microbiota and the Blood Transcriptome in Preterm Infants at Less than 29 Weeks Gestation Diagnosed with Bronchopulmonary Dysplasia
Document Type
article
Source
mSystems, Vol 4, Iss 5 (2019)
Subject
BPD
RNA-Seq
VLBW
fecal organisms
microbiota
neonates
Microbiology
QR1-502
Language
English
ISSN
2379-5077
Abstract
ABSTRACT Bronchopulmonary dysplasia (BPD) is a common chronic lung condition in preterm infants that results in abnormal lung development and leads to considerable morbidity and mortality, making BPD one of the most common complications of preterm birth. We employed RNA sequencing and 16S rRNA gene sequencing to profile gene expression in blood and the composition of the fecal microbiota in infants born at