학술논문

The Octopus Trap of Takotsubo and Stroke: Genetics, Biomarkers and Clinical Management
Document Type
article
Source
Journal of Personalized Medicine, Vol 12, Iss 8, p 1244 (2022)
Subject
Takotsubo cardiomyopathy
stroke
acute stress
genetic susceptibility
biomarkers
Medicine
Language
English
ISSN
2075-4426
Abstract
Takotsubo cardiomyopathy (TC) is a reversible cardiomyopathy mimicking an acute coronary syndrome, usually observed in response to acute stress situations. The association between acute ischemic stroke and TC is already known, since it has been previously reported that ischemic stroke can be both a consequence and a potential cause of TC. However, the precise pathophysiological mechanism linking the two conditions is still poorly understood. The aim of our review is to expand insights regarding the genetic susceptibility and available specific biomarkers of TC and to investigate the clinical profile and outcomes of patients with TC and stroke. Since evidence and trials on TC and stroke are currently lacking, this paper aims to fill a substantial gap in the literature about the relationship between these pathologies.