학술논문

Impact of intralesional botulinum toxin type A therapy on the keloid-related quality of life
Document Type
article
Source
The Egyptian Journal of Otolaryngology, Vol 39, Iss 1, Pp 1-9 (2023)
Subject
Quality of life
Keloid
Head and neck
Arabic adaptation
Botulinum toxin type A
Otorhinolaryngology
RF1-547
Language
English
ISSN
2090-8539
Abstract
Abstract Background We aimed to validate the translated Arabic version of the head and neck keloid quality-of-life (QOL) questionnaire. We also aimed to evaluate the impact of intralesional botulinum toxin type A (BTA) therapy on the keloid-related quality of life. Methods This prospective study included 140 patients with a keloid in the head and neck regions. They were divided into two groups. In Group A, the patient filled out the questionnaire four times: 1 week before the start of the treatment, the first injection (day using intralesional BTA, the second injection day, and 6 months after the first injection. In group B, the patients completed the questionnaires once before any keloid therapy (control group). Results Cronbach’s alpha between all questions was 0.921. The intra-class correlation coefficient between the first and second visits was above 0.8. In Group A, the total score in the first visit was 84.12 ± 5.86, while it was 34.87 ± 3.73 in the fourth fulfilment, with a statistically significant difference between them as the P-value was