학술논문
Recent sarcopenia definitions—prevalence, agreement and mortality associations among men: Findings from population‐based cohorts
Document Type
article
Author
Leo D. Westbury; Charlotte Beaudart; Olivier Bruyère; Jane A. Cauley; Peggy Cawthon; Alfonso J. Cruz‐Jentoft; Elizabeth M. Curtis; Kristine Ensrud; Roger A. Fielding; Helena Johansson; John A. Kanis; Magnus K. Karlsson; Nancy E. Lane; Laetitia Lengelé; Mattias Lorentzon; Eugene McCloskey; Dan Mellström; Anne B. Newman; Claes Ohlsson; Eric Orwoll; Jean‐Yves Reginster; Eva Ribom; Björn E. Rosengren; John T. Schousboe; Eric J. Shiroma; Nicholas C. Harvey; Elaine M. Dennison; Cyrus Cooper; the International Musculoskeletal Ageing Network
Source
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 565-575 (2023)
Subject
Language
English
ISSN
2190-6009
2190-5991
2190-5991
Abstract
Abstract Background The 2019 European Working Group on Sarcopenia in Older People (EWGSOP2) and the Sarcopenia Definitions and Outcomes Consortium (SDOC) have recently proposed sarcopenia definitions. However, comparisons of the performance of these approaches in terms of thresholds employed, concordance in individuals and prediction of important health‐related outcomes such as death are limited. We addressed this in a large multinational assembly of cohort studies that included information on lean mass, muscle strength, physical performance and health outcomes. Methods White men from the Health Aging and Body Composition (Health ABC) Study, Osteoporotic Fractures in Men (MrOS) Study cohorts (Sweden, USA), the Hertfordshire Cohort Study (HCS) and the Sarcopenia and Physical impairment with advancing Age (SarcoPhAge) Study were analysed. Appendicular lean mass (ALM) was ascertained using DXA; muscle strength by grip dynamometry; and usual gait speed over courses of 2.4–6 m. Deaths were recorded and verified. Definitions of sarcopenia were as follows: EWGSOP2 (grip strength