학술논문
Detailed modeling of positive selection improves detection of cancer driver genes
Document Type
article
Author
Source
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Subject
Language
English
ISSN
2041-1723
Abstract
Finding driver genes sheds lights on the biological mechanisms propelling the development of a tumour, and can suggest therapeutic strategies. Here, the authors develop driverMAPS, a model-based approach to identify driver genes, and apply it to TCGA datasets.