학술논문
Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo
Document Type
article
Author
Source
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
The noradrenergic system plays numerous physiological roles but tools to study it are scarce. Here the authors develop a fluorescent analogue of norepinephrine that can be used to label noradrenergic neurons and the synaptic vesicles, and use it to measure single synaptic vesicle release sites in living mice.