학술논문
Myocardial Vasculitis Associated With the Immune Checkpoint Inhibitor Pembrolizumab
Document Type
article
Author
Source
JACC: Case Reports, Vol 2, Iss 12, Pp 1937-1941 (2020)
Subject
Language
English
ISSN
2666-0849
Abstract
Recent developments in immune checkpoint inhibitors (ICIs) have provided new treatment strategies for advanced cancer. However, ICIs lead to an imbalance between T cell–mediated inflammatory responses and immune tolerance in the myocardium. Here we report the first case that implicates the contribution of ICI-induced vasculitis to myocardial injury. (Level of Difficulty: Intermediate.)