학술논문

Progressive Multifocal Leukoencephalopathy after Treatment with Nivolumab
Document Type
article
Source
Emerging Infectious Diseases, Vol 24, Iss 8, Pp 1594-1596 (2018)
Subject
nivolumab
immune checkpoint inhibitor
progressive multifocal leukoencephalopathy
JC virus
viruses
meningtitis/encephalaitis
Medicine
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
1080-6040
1080-6059
Abstract
Progressive multifocal leukoencephalopathy (PML) is increasingly being reported in patients undergoing immunotherapy. We report a case of progressive multifocal leukoencephalopathy after treatment with nivolumab, a PD-1 blocker that is used to restore impaired T-cell responses in patients with cancer and infections. Data for 4 other cases were obtained from pharmacovigilance databases.