학술논문
Endobronchial amphotericin B to treat hemoptysis in an inoperable patient with aspergillosis
Document Type
article
Source
Medical Mycology Case Reports, Vol 43, Iss , Pp 100627- (2024)
Subject
Language
English
ISSN
2211-7539
Abstract
A 37-year-old man presented with chronic cavitary pulmonary aspergillosis and hemoptysis refractory to systemic antifungal therapy with voriconazole and bronchial artery embolization. Surgical excision was unfeasible due to the patient's refusal of blood transfusions. Ten sessions of intracavitary instillation of amphotericin B via flexible bronchoscopy were then performed. Hemoptysis cessation and aspergilloma resolution were achieved, with no toxicity or side effects, and the clinical benefits were sustained at six months of follow-up.