학술논문
Structural and functional analyses explain Pea KAI2 receptor diversity and reveal stereoselective catalysis during signal perception
Document Type
article
Author
Source
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Subject
Language
English
ISSN
2399-3642
Abstract
Guercio et al., combine structural biology, biochemistry, and plant biology to reveal the dual functions of evolutionarily diverged Pisum KAI2A and KAI2B as both receptors and enzymes with distinct ligand selectivity, and propose adaptive sensitivity to strigolactone phytohormones by KAI2B. They reported the structures of KAI2 in apo and ligand intermediate -bound states that further illuminate KAI2s catalysis mechanism.