학술논문
Human immunocompetent choroid-on-chip: a novel tool for studying ocular effects of biological drugs
Document Type
article
Author
Source
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Subject
Language
English
ISSN
2399-3642
Abstract
To address the key physiological characteristics related to choroidal drug reactions and its immunology, Cipriano et al. developed a human immunocompetent choroidal in vitro model that mimics the tissue vascularization, pigmentation and immune response in the presence of circulating immune cells. This could help building a toolbox of in vitro models recapitulating aspects of the immune system to study immuneoncology.