학술논문
Urinary equol levels are positively associated with urinary estradiol excretion in women
Document Type
article
Source
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Subject
Language
English
ISSN
2045-2322
Abstract
Abstract Isoflavones found in soy products are a promising class of nutrients that may have a positive effect on human health. In particular, the phytoestrogen metabolite equol is associated with a reduced risk of developing female hormone-related diseases. However, the effect of equol on estrogen remains unclear. Equol can modify blood and urinary estradiol (E2) levels. The aim of this cross-sectional study was to examine the associations between urinary estrogen levels, equol levels, and equol production status in Japanese women. We analyzed urine samples from 520 women by gas chromatography-mass spectrometry. Urinary E2 and 4-hydroxylated E2 levels were higher in equol producers (EQP) than in non-EQPs (P