학술논문

Assessment of successful percutaneous mitral commissurotomy by MRproANP and sCD146
Document Type
article
Source
BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-9 (2020)
Subject
Mitral stenosis
Biomarker
Brain natriuretic peptide
MRproANP
Diseases of the circulatory (Cardiovascular) system
RC666-701
Language
English
ISSN
1471-2261
Abstract
Abstract Background We studied the course of plasma concentrations of 4 cardiovascular biomarkers: natriuretic peptides (BNP, NT-proBNP; mid-regional (MR) pro-atrial NP); and soluble endothelial CD146 (sCD146), in patients with severe mitral valve stenosis undergoing percutaneous mitral commissurotomy (PMC) to identify potential markers of procedural success. Methods Biomarkers were tested in 40 patients the day before and the day after PMC. Success was defined as mitral valve area ≥ 1.5 cm2; or an increase of ≥0.5 cm2 in mitral valve area associated with echocardiographic mitral regurgitation