학술논문
Impact of Prosthesis‐Patient Mismatch After Surgical Aortic Valve Replacement: Systematic Review and Meta‐Analysis of Reconstructed Time‐to‐Event Data of 122 989 Patients With 592 952 Patient‐Years
Document Type
article
Author
Source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 7 (2024)
Subject
Language
English
ISSN
2047-9980
Abstract
Background It remains controversial whether prosthesis‐patient mismatch (PPM) impacts long‐term outcomes after surgical aortic valve replacement. We aimed to evaluate the association of PPM with mortality, rehospitalizations, and aortic valve reinterventions. Methods and Results We performed a systematic review with meta‐analysis of reconstructed time‐to‐event data of studies published by March 2023 (according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses). Sixty‐five studies met our eligibility criteria and included 122 989 patients (any PPM: 68 332 patients, 55.6%). At 25 years of follow‐up, the survival rates were 11.8% and 20.6% in patients with and without any PPM, respectively (hazard ratio [HR], 1.16 [95% CI, 1.13–1.18], P