학술논문

Systematic screening for advanced liver fibrosis in patients with coronary artery disease: The CORONASH study.
Document Type
article
Source
PLoS ONE, Vol 17, Iss 5, p e0266965 (2022)
Subject
Medicine
Science
Language
English
ISSN
1932-6203
Abstract
Although coronary artery disease (CAD) and advanced liver fibrosis (AdLF) are commonly associated in patients with non-alcoholic fatty liver disease (NAFLD), the prevalence of AdLF and the diagnostic performance of non-invasive fibrosis tests (NITs) in CAD patients remains unknown. We aimed to prospectively screen for AdLF in patients with documented CAD using NITs and Fibroscan. High and intermediate zones of NITs were combined to define AdLF. AdLF was suspected whenever APRI ≥ 0.5, Forns index ≥ 4.2, NAFLD fibrosis score (NFS) ≥ -1.455/0.12 for age