학술논문

Chemical Composition and Biological Properties of Rhododendron anthopogon Essential Oil
Document Type
article
Source
Molecules, Vol 15, Iss 4, Pp 2326-2338 (2010)
Subject
Rhododendron anthopogon
GC-MS
essential oil
antimicrobial activity
topical anti-inflammatory activity
antiproliferative activity
Organic chemistry
QD241-441
Language
English
ISSN
1420-3049
Abstract
The essential oil of Rhododendron anthopogon was investigated by GC-MS, and seventeen compounds (representing approximately 98% of the oil) were identified. The major components of the aerial parts of the oil were the monoterpenes α-pinene, β-pinene, limonene and the sesquiterpene δ-cadinene. Biological studies revealed a weak topical anti-inflammatory activity; a significant killing effect against some Gram-positive reference strains: Staphylococcus aureus, Enterococcusfecalis, Bacillus subtilis was measured; Mycobacterium tuberculosis reference strain and a clinical isolate of Candida, C. pseudotropicalis were killed by as low as 0.04% (v/v) essential oil. Moreover, the oil was able to reduce cancer cell growth independently of the cell line and the treatment protocols used.