학술논문
The effect of NaCl 0.9% and NaCl 0.45% on sodium, chloride, and acid–base balance in a PICU population
Document Type
article
Author
Source
Jornal de Pediatria, Vol 91, Iss 5, Pp 499-505 (2015)
Subject
Language
English
ISSN
0021-7557
Abstract
Objectives: To study the effect of two intravenous maintenance fluids on plasma sodium (Na), and acid–base balance in pediatric intensive care patients during the first 24 h of hospitalization. Methods: A prospective randomized controlled study was performed, which allocated 233 patients to groups: (A) NaCl 0.9% or (B) NaCl 0.45%. Patients were aged 1 day to 18 years, had normal electrolyte concentrations, and suffered an acute insult (medical/surgical). Main outcome measured: change in plasma sodium. Parametric tests: t-tests, ANOVA, X2 statistical significance level was set at α = 0.05. Results: Group A (n = 130): serum Na increased by 2.91 (±3.9) mmol/L at 24 h (p