학술논문
Immunotherapy and Cancer: The Multi-Omics Perspective
Document Type
article
Author
Source
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3563 (2024)
Subject
Language
English
ISSN
1422-0067
1661-6596
1661-6596
Abstract
Immunotherapies have revolutionized cancer treatment approaches. Because not all patients respond positively to immune therapeutic agents, it represents a challenge for scientists who strive to understand the mechanisms behind such resistance. In-depth exploration of tumor biology, using novel technologies such as omics science, can help decode the role of the tumor immune microenvironment (TIME) in producing a response to the immune blockade strategies. It can also help to identify biomarkers for patient stratification and personalized treatment. This review aims to explore these new models and highlight their possible pivotal role in changing clinical practice.