학술논문
Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study
Document Type
article
Author
Niccolò Buetti; Alexis Tabah; Ambre Loiodice; Stéphane Ruckly; Abdullah Tarik Aslan; Giorgia Montrucchio; Andrea Cortegiani; Nese Saltoglu; Bircan Kayaaslan; Firdevs Aksoy; Akova Murat; Özlem Akdoğan; Kemal Tolga Saracoglu; Cem Erdogan; Marc Leone; Ricard Ferrer; José-Artur Paiva; Yoshiro Hayashi; Mahesh Ramanan; Andrew Conway Morris; François Barbier; Jean-François Timsit; the Eurobact 2 study group
Source
Critical Care, Vol 26, Iss 1, Pp 1-12 (2022)
Subject
Language
English
ISSN
1364-8535
Abstract
Abstract Background The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 and non-COVID-19 critically ill patients. Methods We used data from the Eurobact II study, a prospective observational multicontinental cohort study on HABSI treated in ICU. For the current analysis, we selected centers that included both COVID-19 and non-COVID-19 critically ill patients. We performed descriptive statistics between COVID-19 and non-COVID-19 in terms of patients’ characteristics, source of infection and microorganism distribution. We studied the association between COVID-19 status and mortality using multivariable fragility Cox models. Results A total of 53 centers from 19 countries over the 5 continents were eligible. Overall, 829 patients (median age 65 years [IQR 55; 74]; male, n = 538 [64.9%]) were treated for a HABSI. Included patients comprised 252 (30.4%) COVID-19 and 577 (69.6%) non-COVID-19 patients. The time interval between hospital admission and HABSI was similar between both groups. Respiratory sources (40.1 vs. 26.0%, p