학술논문

Humoral response to SARS-CoV-2 after vaccination and booster effect in patients undergoing dialysis
Document Type
article
Source
International Journal of Infectious Diseases, Vol 122, Iss , Pp 327-331 (2022)
Subject
Vaccine
SARS-CoV-2
IgG RBD
Booster effect
Dialyzed patients
BNT162b2
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
1201-9712
Abstract
Objective: The aim of this study was to determine and evaluate the postvaccination variation in immunoglobulin G (IgG) receptor-binding domain (RBD) produced in non-SARS-CoV-2–infected patients with nephropathy and renal replacement therapy. Methods: This is a follow-up study of the humoral response to the BNT162b2 messenger ribonucleic acid COVID-19 vaccine in patients with nephropathy, comparing it with itself at different times and with the healthy population. Results: In patients with nephropathy, a very striking decrease in IgG RBD was observed compared with the healthy population (P