학술논문
KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells
Document Type
article
Author
Source
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Subject
Language
English
ISSN
2399-3642
Abstract
KLF4-induced phenotypic switching of vascular smooth muscle cells occurs in atherosclerosis. Now, KLF4 is shown to induce a glycolytic shift involving upregulation of PFKFB3 expression through circular RNA CTDP1 and eukaryotic elongation factor eEF1A2.