학술논문

Airflow obstruction as a marker of adverse prognosis in rheumatoid arthritis
Document Type
article
Source
Frontiers in Medicine, Vol 10 (2023)
Subject
rheumatoid arthritis
airway obstruction
chronic obstructive pulmonary disease
interstitial lung diseases
bronchiolitis
Medicine (General)
R5-920
Language
English
ISSN
2296-858X
Abstract
ObjectivesIn our study, we explored the specific subgroup of patients with rheumatoid arthritis (RA) suffering from obstructive lung disease (OLD) and its impact on morbi-mortality.MethodsOur retrospective study included 309 patients suffering from RA with either obstructive (O-RA) or non-obstructive patterns (non-O-RA). OLD was defined based on the Tiffeneau index at the first available pulmonary functional test (PFT). Survival was then calculated and represented by a Kaplan–Meier curve. The comparison between the populations considered was performed by the Log-Rank test.ResultsOut of the 309 RA patients, 102 (33%) had airway obstruction. The overall survival time was significantly lower in the O-RA group than in the non-O-RA group (n = 207) (p