학술논문
A case of development of autoimmune pulmonary alveolar proteinosis during the treatment of hypersensitivity pneumonitis
Document Type
article
Author
Source
Respiratory Medicine Case Reports, Vol 44, Iss , Pp 101862- (2023)
Subject
Language
English
ISSN
2213-0071
Abstract
Herein, we report the case of a 73-year-old woman with an occupational history of plaster grinding who developed autoimmune pulmonary alveolar proteinosis (PAP) during the treatment of fibrotic hypersensitivity pneumonitis with steroids and immunosuppressive drugs. Based on the changes in computed tomography imaging findings, poor response to steroid therapy, and markedly elevated KL-6 levels, PAP was suspected and diagnosed by bronchoscopy. Repeated segmental bronchoalveolar lavage under high-flow nasal cannula oxygen therapy resulted in slight improvement. Steroids and immunosuppressive treatments for other interstitial lung diseases may cause PAP or exacerbate latent PAP.