학술논문

Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay
Document Type
article
Source
New Microbes and New Infections, Vol 4, Iss C, Pp 1-4 (2015)
Subject
Cryptococcus neoformans
HIV
immunochromatography
meningitis
Antigen test
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
2052-2975
Abstract
Detection of cryptococcal antigen in serum or cerebrospinal fluid allows cryptococcal meningitis diagnosis within few hours with >90% sensitivity. In an HIV-positive patient with Cryptococcus neoformans meningitis, initial antigen detection by immunoagglutination was negative. We thus evaluated a new immunochromatographic detection assay that exhibited a higher sensitivity.