학술논문
Bacterial co-infection at hospital admission in patients with COVID-19
Document Type
article
Author
Estela Moreno-García; Pedro Puerta-Alcalde; Laura Letona; Fernanda Meira; Gerard Dueñas; Mariana Chumbita; Nicole Garcia-Pouton; Patricia Monzó; Carlos Lopera; Laia Serra; Celia Cardozo; Marta Hernandez-Meneses; Verónica Rico; Marta Bodro; Laura Morata; Mariana Fernandez-Pittol; Ignacio Grafia; Pedro Castro; Josep Mensa; José Antonio Martínez; Gemma Sanjuan; Mª Angeles Marcos; Alex Soriano; Carolina Garcia-Vidal
Source
International Journal of Infectious Diseases, Vol 118, Iss , Pp 197-202 (2022)
Subject
Language
English
ISSN
1201-9712
Abstract
ABSTRACT: Objectives: We described the current incidence and risk factors of bacterial co-infection in hospitalized patients with COVID-19. Methods: Observational cohort study was performed at the Hospital Clinic of Barcelona (February 2020–February 2021). All patients with COVID-19 who were admitted for >48 hours with microbiological sample collection and procalcitonin (PCT) determination within the first 48 hours were included. Results: A total of 1125 consecutive adults met inclusion criteria. Co-infections were microbiologically documented in 102 (9.1%) patients. Most frequent microorganisms were Streptococcus pneumoniae (79%), Staphylococcus aureus (6.8%), and Haemophilus influenzae (6.8%). Test positivity was 1% (8/803) for blood cultures, 10.1% (79/780) for pneumococcal urinary antigen test, and 11.4% (15/132) for sputum culture. Patients with PCT higher than 0.2, 0.5, 1, and 2 ng/mL had significantly more co-infections than those with lower levels (p=0.017, p=0.031, p94%.