학술논문
Sex Disparities and Neutralizing-Antibody Durability to SARS-CoV-2 Infection in Convalescent Individuals
Document Type
article
Author
Alena J. Markmann; Natasa Giallourou; D. Ryan Bhowmik; Yixuan J. Hou; Aaron Lerner; David R. Martinez; Lakshmanane Premkumar; Heather Root; David van Duin; Sonia Napravnik; Stephen D. Graham; Quique Guerra; Rajendra Raut; Christos J. Petropoulos; Terri Wrin; Caleb Cornaby; John Schmitz; JoAnn Kuruc; Susan Weiss; Yara Park; Ralph Baric; Aravinda M. de Silva; David M. Margolis; Luther A. Bartelt
Source
mSphere, Vol 6, Iss 4 (2021)
Subject
Language
English
ISSN
2379-5042
Abstract
In this study, we found that neutralizing antibody responses in COVID-19-convalescent individuals vary in magnitude but are durable and correlate well with receptor binding domain (RBD) Ig binding antibody levels compared to other SARS-CoV-2 antigen responses. In our cohort, higher neutralizing antibody titers are independently and significantly associated with male sex compared to female sex.