학술논문
Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
Document Type
article
Author
Nikaïa Smith; Nicolas Pietrancosta; Sophia Davidson; Jacques Dutrieux; Lise Chauveau; Pasquale Cutolo; Michel Dy; Daniel Scott-Algara; Bénédicte Manoury; Onofrio Zirafi; Isabelle McCort-Tranchepain; Thierry Durroux; Françoise Bachelerie; Olivier Schwartz; Jan Münch; Andreas Wack; Sébastien Nisole; Jean-Philippe Herbeuval
Source
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Subject
Language
English
ISSN
2041-1723
Abstract
Plasmacytoid dendritic cells produce type I interferons in response to viral sensing. Here the authors show that amines inhibit these plasmacytoid dendritic cell responses through CXCR4 engagement.