학술논문
Incidental Congestive Heart Failure in Patients With Aldosterone‐Producing Adenomas
Document Type
article
Author
Source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 24 (2019)
Subject
Language
English
ISSN
2047-9980
Abstract
Background Previous studies show that patients with primary aldosteronism are associated with higher risk of congestive heart failure (CHF). However, the effect of target treatment to the incidental CHF has not been elucidated. We aimed to investigate the risk of new‐onset CHF in patients with aldosterone‐producing adenomas (APAs) and explore the effect of adrenalectomy on new onset of CHF. Methods and Results From 1997 to 2009, 688 APA were identified and matched with essential hypertension controls. The risks of developing incidental CHF (hazard ratio, 0.49; 95% CI, 0.31–0.75; P=0.001) and mortality (hazard ratio, 0.29; 95% CI, 0.20–0.44; P