학술논문
The Effects of Thiamine Supplementation on General Health and Infertility Treatment Outcomes in Women with Polycystic Ovary Syndrome: A Triple-Blinded Randomized Placebo-Controlled Clinical Trial
Document Type
article
Source
International Journal of Fertility and Sterility, Vol 18, Iss 2, Pp 128-134 (2024)
Subject
Language
English
ISSN
2008-076X
2008-0778
2008-0778
Abstract
Background: The aim of this study was to evaluate the effects of thiamine (vitamin B1) on general health and infertilitytreatment outcomes in women with polycystic ovary syndrome (PCOS).Materials and Methods: The study is a triple-blinded, randomized, placebo-controlled clinical trial performed on 64 infertilewomen with PCOS referred to Sarem Hospital in Tehran, Iran. The primary outcomes of the study were general healthand infertility treatment outcomes. Eligible women were randomly assigned to the vitamin B1 group (n=32, vitamin B1tablet at a dose of 300 mg/day for 4 weeks) or the placebo group (n=32, placebo tablet daily for 4 weeks). A general healthquestionnaire was completed before and after the intervention by both groups and treatment success was evaluated at theend of the study. Data were analyzed using SPSS software ver.16 P