학술논문

Influences of Neural Pathway Integrity in Children's Response to Reading Instruction
Document Type
article
Source
Frontiers in Systems Neuroscience, Vol 4 (2010)
Subject
Diffusion Tensor Imaging
Magnetic Resonance Imaging
connectivity
Children
Probabilistic Tractography
Response to Intervention
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Language
English
ISSN
1662-5137
Abstract
As the education field moves toward using responsiveness to intervention (RTI) to identify students with disabilities, an important question is the degree to which this classification can be connected to a student’s neurobiological characteristics. A few functional neuroimaging studies have reported a relationship between activation and response to instruction; however, whether a similar correlation exists with white matter (WM) is not clear. To investigate this issue, we acquired high angular resolution diffusion images from a group of first grade children who differed in their levels of responsiveness to a year-long reading intervention. Using probabilistic tractography, we calculated the strength of WM connections among nine cortical regions of interest and correlated these estimates with participants’ scores on four standardized reading measures. We found eight significant correlations, four of which were connections between the insular cortex and angular gyrus. In each of the correlations, a relationship with children’s response to intervention was evident.