학술논문

Probable Hydrocephalus Decompensation after Immunization with Pentavalent Vaccine: Case Report and Literature Review
Document Type
article
Source
Brazilian Neurosurgery, Vol 41, Iss 03, Pp e275-e282 (2022)
Subject
pentavalent vaccine
hydrocephalus
arachnoid cyst
inflammation
blood-cerebrospinal fluid barrier
neuroendoscopy
Medicine
Surgery
RD1-811
Language
English
ISSN
0103-5355
2359-5922
Abstract
There are several complications associated with immunization with the pentavalent vaccine. Most of them are mild reactions, of spontaneous resolution; however, though rare, serious and potentially-fatal adverse effects can occur. We report a case of acute intracranial hypertension syndrome in an infant with a previously-unknown suprasellar arachnoid cyst who developed acute obstructive hydrocephalus after immunization with the pentavalent vaccine. He underwent neuroendoscopic treatment, showing complete resolution of the condition. The present article aims to compare the activation of the immune system by the pertussis component of the vaccine and the mechanisms that hypothetically potentiated the pathological decompensation.