학술논문

Emerging heterogeneous compartments by viruses in single bacterial cells
Document Type
article
Source
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
Here, the authors apply live-cell and in situ fluorescence imaging at the single-molecule level to examine lambda DNA replication in single cells, finding that individual phage DNAs sequester host factors to their own vicinity and confine their replicated DNAs into separate compartments, suggesting that phage decision-making transcripts are spatially organized in separate compartments to allow distinct subcellular decisions to develop.