학술논문
The usefulness of C-reactive protein to predict improving left ventricular function after aortic valve replacement in patients with aortic regurgitation
Document Type
article
Author
Hiroki Usuku; Fumi Oike; Eiichiro Yamamoto; Naoko Kai; Koichi Egashira; Takashi Komorita; Kyoko Hirakawa; Shozo Kaneko; Noriaki Tabata; Masanobu Ishii; Kenshi Yamanaga; Koichiro Fujisue; Shinsuke Hanatani; Tadashi Hoshiyama; Hisanori Kanazawa; Daisuke Sueta; Yuichiro Arima; Seiji Takashio; Hiroaki Kawano; Kenichi Matsushita; Toshihiro Fukui; Hirotaka Matsui; Kenichi Tsujita
Source
American Heart Journal Plus, Vol 17, Iss , Pp 100169- (2022)
Subject
Language
English
ISSN
2666-6022
Abstract
Background: We aimed to clarify the predictive factors for left ventricular (LV) function after aortic valve replacement (AVR) in patients with aortic regurgitation (AR). Methods and results: Among 555 patients who underwent AVR at our institution from January 2015 to December 2020, we enrolled 44 patients for whom only AVR (or AVR + aortic replacement) was performed. We defined LV dysfunction under any of the following criteria: LV ejection fraction (LVEF) 65 mm, LV systolic dimension (LVDs) >50 mm, or LVDs/body surface area > 25 mm/m2. Multivariable logistic regression analysis revealed high natural logarithm (ln) C-reactive protein (CRP) and low LVEF in the pre-AVR period significantly associated with LV dysfunction after AVR (ln CRP: odds ratio [OR] 4.15, 95 % confidence interval [CI] 1.44–11.98, p